The Midwest Hiawatha was a passenger train service of the Milwaukee Road. The service was inaugurated in the 1930s to operate between Chicago's Union Station and Omaha, Nebraska, through Iowa. The train was successful despite bypassing every major city in Iowa.
The train was discontinued when the Milwaukee Road assumed operation of Union Pacific Railroad's City of San Francisco, City of Los Angeles, City of Denver, City of Portland and Challenger trains in 1955. The UP/Milwaukee transcontinental service operated over the same route as the former Midwest Hiawatha until 1971 when Amtrak selected the Chicago, Burlington and Quincy Railroad's route across Iowa for its California Zephyr transcontinental services.